Whole-Brain Ultrastructural Mapping

We are mapping the whole mouse brain ultrastructurally using serial blockface electron microscopy. Stay tuned!

Example data

This is a whole-brain blockface image from the mouse brain taken at 80 nm pixel size. Click on the thumbnail to view:

Select Publications

Mikula, S., Binding, J., Denk, W. Staining and Embedding the Whole Mouse Brain for Electron Microscopy. Nature Methods 9, 1198–1201 (2012) (DOI:10.1038/NMETH.2213)

Binding, J., Mikula, S., Denk, W. Low-dosage maximum-a-posteriori focusing and stigmation (MAPFoSt). Microscopy and Microanalysis. (2012, In Press).


Shawn Mikula, Ph.D.
Max-Planck Institute for Medical Research
Department of Biomedical Optics
Jahn-Str. 29, D-69120 Heidelberg, Germany

Further Information

www.connectomes.org - Whole-Brain Circuit Reconstruction